Shenzhen Liying Biotechnology Co., Ltd. is a synthetic biology enterprise, founded in April 2022 and registered in Guangming District, Shenzhen. It mainly focuses on providing design and transformation services, production and sales of biological manufacturing products through cutting-edge artificial intelligence technology and structural biology, and can provide high-quality protein raw materials and technical transformation services to various industries in various application scenarios. The company has built six core technology platforms, namely, artificial intelligence-assisted protein design platform, high-throughput structural biology platform, single B cell high-performance antibody discovery platform, production-end strain modification platform, protein raw material matching screening and verification platform, GMP pilot production, which can optimize protein modification from the sequence-structure-function level. In 2023, the core team of Liying Biology conquered the technology of triple-helix collagen with thermal stability, becoming the first enterprise in the industry to achieve efficient expression and low-cost mass production of triple-helix collagen. In December 2025, the public service platform of "Proteincraft" AI + bio-manufacturing "was officially released, and a one-stop service platform of" calculation-design-verification-optimization "was built. At present, the company has applied for more than 30 Chinese invention patents (10 of which have been authorized) and 5 international PCT and overseas invention patents; it has obtained the qualification recognition of specialized, special and new, national high-tech enterprises, seed unicorns, synthetic biology cutting-edge enterprises, and won many awards such as the first prize of the 11th "Huachuang Cup" entrepreneurship competition in international competitions.

The first painless and comfortable ultrasonic scalpel equipment in China was approved for facial indications in July 2025. The ultrasonic therapeutic instrument (II) uses the energy of ultrasonic waves to help tighten and lift facial skin and remove wrinkles without tissue degeneration. The technical advantage lies in mastering the core technology of precise energy delivery, solving the problems of strong pain and unstable effect of traditional ultrasonic scalpel equipment, and improving user experience and treatment safety. With its precise energy delivery technology and excellent performance, the equipment has been highly recognized by the market and has become a popular choice for medical and aesthetic institutions.

Through the method of biosynthesis, combined with artificial intelligence calculation, design and transformation, high activity protein was obtained and high adaptive engineering bacteria were constructed. The triple helix collagen protein has stable structure, strong efficacy and good biocompatibility, has significant anti-aging, repair, anti-wrinkle and whitening effects, and can be applied not only in the fields of skin care and daily chemicals, but also in clinical medicine, such as medical and aesthetic filling, wound repair, orthopaedics and other fields. In addition, the high temperature resistant property of the recombinant humanized collagen enables the recombinant humanized collagen to adapt to various production and application environment strains, and the successful expression and efficient production of the recombinant humanized collagen with a triple helix structure are realized

As an innovator in the IVD core raw material field, we focus on providing customers with raw material solutions beyond the conventional ones through cutting-edge protein structure design technology. Excellent IVD performance begins with excellent molecules. With the deep integration of protein rational design and artificial intelligence prediction, we can accurately optimize the structure and function of traditional diagnostic markers (such as antigens, antibodies, enzymes). This is not a simple production, but a "gene-level" modification at the molecular level to achieve breakthroughs in key attributes such as multivalent binding, epitope specificity, catalytic efficiency or stability. Our technology can systematically solve the industry pain points such as insufficient sensitivity and high cross-reaction, and upgrade the performance of raw materials to new standards.
AI + biological manufacturing pilot platform, customized services for protein modification, recombinant collagen products for Class II medical devices, recombinant humanized collagen raw materials, ultrasonic scalpel equipment for Class II medical devices, cosmetic products (collagen essence water, collagen cream, suspended oil polishing essence, etc.)